孟雁

公卫家园

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研究方向与目前进展 公卫家园

疾病的分子遗传学；基因结构、功能及表达调控；重点为糖尿病、肥胖及代谢综合征的分子致病机理；药物筛选平台的建立及新药开发；转基因动物模型制作及解析。

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  公卫百科

主要学习及工作简历

公卫百科

社会任职 公卫家园

中国医科大学客座教授, 北京生理学会理事，“生理通讯”常务副主编

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代表性学术论文

代表性论著：（*通讯作者）

公卫家园

1. Liu LZ, Zhao HL, Zuo J, Ho SK, Chan JC, Meng Y*, Fang FD, Tong PC. PKC {zeta} Mediates Insulin-induced Glucose Transport through Actin Remodeling in L6 Muscle Cells. Mol Biol Cell, 2006.17(5):2322-30. 公卫论坛

2. Yan Meng, Miyoshi I., et al. Restoration of copper metablism and rescue of hepatic abnormalities in LEC Rat, an animal model of Wilson disease by expression of Human ATP7B. Biochim Biophys Acta. 2004.1690: 208-219.

3. Yun-Feng Li, Guo-Dong Wu, Hong-Xia Sun, Wei-Nan Du, Jin Zuo, Yan Shen, Bo-Qin Qiang, Zhi-Jian Yao, Heng Wang, Wei Huang, Zhu Chen, Mo-Miao Xiong, Yan Meng*, Fu-De Fang. Protein Kinase C/ζ(PRKCZ) is Associated with Type 2 Diabetes in Han Population of Northern China and Analysis of its Haplotype. World Journal of Gastroenterology, 2003， 9（9）2078-2082. 公卫论坛

4. Zhuo Liu, Hong-Xia Sun, Yong-Wei Zhang, Yun-Feng Li, Jin Zuo, Yan Meng*, Fu-De Fang. Effect of SNPs in Protein Kinase Cz Gene on Gene Expression in the Reporter Gene Detection System. World Journal of Gastroenterology, 2004;10(16):2357-2360.

5. Yasumasa Mototani, Ichiro Miyoshi, Tadashi Okamura, Takuya Moriya, Yan Meng, Xiang Yuan Pei, Satomi Kameo and Noriyuki Kasai. Phenotypic and genetic characterization of the Atp7aMo-Tohm mottled mouse: A new murine model of Menkes disease .Genomics, 2006; 87(2) : 191-199. 公卫论坛

6. Feng Qi-Ping, Zuo Jin, Meng Yan*, Fang Fu-De .nuclear localization region in soluble adenylyl cyclase. Acta Acad Med Sini. 2005，27（3）：280－284.

公卫考场

7. Li Yi, Zuo Jin, Meng Yan*, Fang Fu-De. Screening susceptibility genes of type 2 diabetes in Chinsese population by SNP analysis. Acta Acad Med Sini，2005，27（3）：272－279.

8. Wei Cao, Jin Zuo, Yan Meng, Qiang Wei, Zhaohui Shi, Limei Ju, Fude Fang. Anticancer Drug Resistance of HeLa Cells Transfected with Rat Glutathione S-transferase pi gene. Biomed. Environ. Sci. 2003，16：157-162。

9. Liu J, Zhao X, Meng Yan, Shen J, Xue Y, Shi S, Cai Y. Expression and deletion analysis of EcoRII endonuclease and methylase gene. Chin Med Sci J. 2001 Dec;16(4):200-3. 公卫论坛

10. YunFeng Li, YongSheng Chang Lifeng Zhang, Qiping Feng,Zhuo Liu, Yongwei Zhang, Jin Zuo, Yan Meng and Fu-De Fang. High glucose upregulates pantothenate kinase 4 (PANK4) thus affectes M2- type pyrvatekinase (Pkm2). Molecular and Cellular Biochemistry , 277 (1-2)：117-125, 2005。 公卫人

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