梅品超

公卫家园

研究方向及目前进展 公卫论坛

1.Molecular Mechanisms of Histone/DNA Demethylation (Histone/DNA Demethylase) 
2.Molecular Basis of Epigenetic Inheritance 公卫家园

本实验室成立于2008年，研究兴趣集中于表观遗传调控的分子机制。目前的重点在于寻找新的组蛋白去甲基化酶和组蛋白作用蛋白。 公卫考场

  公卫人

主要学习及工作简历

  公卫考场

代表性学术论文 公卫百科

1. Rui Fang, Andrew J. Barbera, Yufei Xu, Michael Rutenberg, Thiago Leonor, Qing Bi, Fei Lan, Pinchao Mei, Guo-Cheng Yuan, Christine Lian, Junmin Peng, Dongmei Cheng, Guangchao Sui, Ursula B. Kaiser, Yang Shi and Yujiang Geno Shi. Human LSD2/KDM1b/AOF1 regulates gene transcription by modulating intragenic H3K4me2 methylation. Molecular Cell, 2010, 39: 222-233.

2. Liu Yu*, Yang Wang*, Shuo Huang*, Jianjun Wang, Zengqin Deng, Qi Zhang, Wei Wu, Xingliang Zhang, Zhao Liu, Weimin Gong, Zhongzhou Chen. Cell Research, 2010, 20: 166-173. (*: co-firsr authors)

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3. Mamta Tahiliani*, Pinchao Mei*, Rui Fang, Thiago Leonor, Michael Rutenberg, Fumiko Shimizu, Jing Li, Anjana Rao, Yujiang Shi. The histone H3K4 demethylase SMCX links REST target genes to X-linked mental retardation. Nature, 2007, 447: 601-605.

公卫人

4. Jianmin Liu, Sherry L. Ball, Yuan Yang, Pinchao Mei, Lei Zhang, Haining Shi, Henry J. Kaminski, Vance P. Lemmon and Huaiyu Hu. A genetic model for muscle-eye-brain disease in mice lacking protein O-mannose 1,2-N-acetylglucosaminyltransferase (POMGnT1). Mechanisms of Development, 2006, 123: 228-240. 公卫家园

5. Jianmin Liu, Lei Zhang, Dongmei Wang, Huaming Shen, Min Jiang, Pinchao Mei, Patrick S. Hayden, John R. Sedor and Huaiyu Hu. Congenital diaphragmatic hernia, kidney agenesis and cardiac defects associated with Slit3-deficiency in mice. Mechanisms of Development, 2003, 120: 1059-1070. 公卫论坛

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