李克

李克、男、博士学历、教授、博士生导师、汕头大学医学院公共卫生与预防医学教研室主任。 公卫人

公卫人

1997年于上海医科大学公共卫生学院博士毕业，讲授的本科和研究生课程主要有预防医学、医学统计学、循证医学、消化与营养、多元统计与软件、临床科研方法设计、流行病学原理、分子流行病学等课程。担任广东省医学会卫生学会常委、汕头市预防医学会常务理事、汕头市环境科学学会常务理事等社会学术团体职务。主要研究方向为肿瘤流行病学和分子流行病学，承担和参加课题主要有教育部课题《应用生物标志物鉴别个体食管癌危险度》、日本文部省合作课题《中、日、韩消化道肿瘤危险因素和保护因素的比较性研究》、广东省科技计划项目《潮汕地区食物金标准数据库的建立和食物半定量调查表的开发研究》、广东省医学科研基金《食管/贲门癌高发区高危人群中促进肿瘤早期诊断的健康教育和干预》、国家自然科学基金《肝癌易感、生长特性的时间生物学研究》等，曾获江西省科学进步三等奖。在SCI收录杂志发表论文近20篇，主编论著一部。代表性论文论著如下：

公卫论坛

1. Li Ke, Yu Shunzhang. Economic status, smoking, occupational exposure to rubber, and lung cancer: A case-cohort study. J Environ Sci Health C-Envir. 2002; 20: 21-28. 公卫人

2. Li Ke, Yu Shunzhang. Leukemia mortality and occupational exposure to rubber: A nested case-control study. Int J Hyg Environ Health. 2002; 204: 317-321. 公卫家园

3. Li Ke, Yu Shunzhang. A nested case-control study on risk of pancreatic cancer among workers in the rubber industry. Pancreas. 2002; 24: 417-418,7.

公卫百科

4. Li Ke. Mortality in a Chinese rubber factory: A prospective cohort study. J Occup Health.  2002; 44: 76-82.

公卫论坛

5. Li Ke, Yu Shunzhang. Novel epidemiologic evidence for the association between fermented fish sauce and esophageal cancer in South China. Int J Cancer. 2002; 99: 424-426. 公卫考场

6. Li Ke, Yu Shunzhang. Oesophageal cancer and occupational exposure to rubber: a nested case-control study. Ann Occup Hyg. 2000; 44: 355-359. 公卫家园

7. Li Ke, Yu Shunzhang. Economic status and occupational correlates of stomach cancer in the rubber industry. Int J Occup Med Environ Health. 1999; 12: 345-352.

8. Ke L, Yu P, Zhang ZX, Huang SS, Huang G, Ma XH. Congou tea drinking and oesophageal cancer in South China. Brit J Cancer. 2002; 86: 346-347.

公卫论坛

9. Li Ke. Mortality and incidence trends from esophagus cancer in selected geographic areas of China circa 1970-90. Int J Cancer. 2002; 102: 271-274. 公卫人

10. Li K, Yu P. Food groups and risk of esophageal cancer in Chaoshan region of China: A high-risk area of esophageal cancer. Cancer Investigation.2003; 21: 231–234. 公卫考场

11. Ke L, Ping Y, Ge H. Epidemiological study of risk factors of esophageal cancer in South China. Cancer Epidemiology Biomarkers & Prevention. 2002; 11: PD130.

公卫论坛

12. Ke L, Ping Y, Ge H. Protective action of fresh fruit and vegetable consumption on the synergic effect of alcohol and tobacco use on esophageal cancer in south China. Nutrition. 2003; 19: 821. 公卫考场

13. Song FY, Toshiro T, Li K, Yu P, Lin XK, Yang HL, Deng XL, Zhang YQ, Lv LW, Huang XE, Kazuo T. Development of a semi-quantitative food frequency questionnaire for middle-aged inhabitants in the Chaoshan area, China. World J Gastroenterol. 2005; 11: 4078-4084. (Corresponding author)

公卫论坛

14. Ke L, Toshiro T, Fengyan S, Ping Y, Xiaoling D, Kazuo T. Relative Validity of a Semi-quantitative Food Frequency Questionnaire Versus 3 day Weighed Diet Records in Middle-aged Inhabitants in Chaoshan Area, China. Asian Pac J Cancer Prev. 2005; 6: 376-81.

15. Li K, Takezaki T, Lv LW, Yu P, Song FY, Tajima K. Reproducibility of a semi-quantitative food frequency questionnaire in Chaoshan area, China. Asian Pac J Cancer Prev. 2005; 6: 521-526.

公卫人

16. Li K, Takezaki T, Song FY, Yu P, Lin XK, Yang HL, Deng XL, Zhang YQ, Lv LW, Huang XE, Tajima K. The KOJACH food frequency questionnaire for Chaoshan, China: development and description. Asia Pac J Clin Nutr. 2006; 15: 153-160.  

17. Li Ke, Zhang Yu Qi, Yu Ping and Cheng Yi Ren. Effect of SNP at position 40237 in exon 7 of the TPH2 gene on susceptibility to suicide. Brain Research. 2006;1122(1):24-26. 公卫家园

18. Changsong Zhang, Zhengyou Li, Yue Cheng, FengqiJia, Rong Li, Mengchao Wu, Ke Li, Lixin Wei1. CpGIslandMethylator PhenotypeAssociation with Elevated Serum A-Fetoprotein Level in Hepatocellular Carcinoma. Clin Cancer Res. 2007;13: 944-952. (Instructorr)

19. Zhang C, Li K, Wei L, Li Z, Yu P, Teng L, Wu K, Zhu J. p300 expression repression by hypermethylation associated with tumour invasion and metastasis in oesophageal squamous cell carcinoma. J Clin Pathol. 2007; 60: 1249-1253. (Corresponding author)

公卫家园

20. Wu K, Li K. Association between esophageal cancer and drought in China by using Geographic Information System. Environ Int.. 2007; 33: 603-608. (Instructorr)

公卫论坛

21. 李克 主编. 临床科研方法-原则与纲要. 江西科学技术出版社, 2003.