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周宏伟

周宏伟,博士,环境卫生学副教授。现任环境卫生学科室主任,环境卫生学系学科带头人,International Society for Microbial Ecology 会员。
研究方向

(1)微生物组方法学(2)人体微生物组(3)环境微生物组

公卫家园

科研项目

“基于Solexa深度测序的高通量、低成本微生物多样性研究方法的建立与优化”——国家自然科学基金
“抗生素耐药基因污染的环境行为研究”——广东省自然科学基金
“低浓度抗生素污染的环境耐药性风险研究”——教育部高等学校博士学科点专项科研基金

公卫论坛


“高通量、低成本测定微生物群落结构新方法研究”——院长基金
“某药物生物安全质量体系建立”——企业横向
“食品安全相关毒素的制备”——企业横向 公卫百科

执行中课题(课题负责人)

(1)国家自然科学基金面上项目"基于BIPES的微生物群落分析新方法研究"(31270152),82万元,起止年份2013-2016;
(2)教育部“新世纪优秀人才”(NCET-11-0921),50万元,2011年11月获得;
(3)国际海域资源调查与开发“十二五”重大课题子课题"深海资源微生物多样性分析及数据库建设"(DY125-15-R-01),80万元,起止年份2012-2015;

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(4)南方医科大学国家杰出青年科学基金培育计划,30万元,起止年份2011-2013;
(5)广东省自然基金面上项目“高通量测序分析微生物群落结构的关键技术研究”(S2011010004136),5万元,执行年份2012-2013;
(6)广东省教育厅科研处科技创新项目“微生物群落结构分析新方法的实验偏差研究”(2012KJCX0031),14万元,执行年份2013-2014; 公卫百科

  公卫百科

代表论文


第一作者
(1) Zhou HW, Wong HY, Yu MK, Park YD, Wong YS and Tam NF (2009) Polycyclic Aromatic Hydrocarbon-Induced Structural Shift of Bacterial Communities in Mangrove Sediment. Microbial Ecology 58: 153-160 公卫百科
(2) Zhou HW, Luan TG, Zou F, Tam NF. (2008) Different bacterial groups for biodegradation of three- and four-ring PAHs isolated from a Hong Kong mangrove sediment. Journal of Hazardous Materials 152, 1179-1185
(3) Zhou, HW, Guo, CL, Wong, YS and Tam, NFY (2006) Genetic diversity of dioxygenase genes in PAH-degrading bacteria isolated from mangrove sediments. FEMS Microbiology Letters, 262, 148-157.

公卫百科

(4) Zhou, HW, Park, YD, and Zhou, HM (2002) Lead ion effect on creatine kinase: equilibrium and kinetic studies of inactivation and conformational changes. International Journal of Biochemistry and Cell Biology 34(5):564-71.
(5) Zhou, HW, Xu, Y, and Zhou, HM (2002) Activity and conformational changes of horseradish peroxidase in trifluoroethanol Biochemistry and Cell Biology. 80:205-13. 公卫人

通讯作者
公卫人

(1) Zhou HW*, Li DF, Tam NF, Jiang XT, Zhang H, Sheng HF, Liu X, Qin J, and Zou F (2010) Barcoded Illumina Paired-End Sequencing, a Cost-Effective High-Throughput Method for Assessing Microbial Diversity. The ISME Journal (通讯作者,已接受 IF 6.39) 公卫考场
(2) Lu SY, Zhang YL, Gen SN, Li TY, Ye ZM, Zhang DS, Zou F and Zhou HW* (2010) High Diversity of Extended-spectrum Beta-lactamase-producing Bacteria in an Urban River Sediment Habitat. Applied and Environmental Microbiology 76: 5972-5976. (通讯作者,IF 3.686) 公卫论坛
(3) Lv ZR, Shi L, Wang J, Park D, Bhak J, Yang JM, Park YD, Zhou HW* and Zou F* (2010) The effect of trifluoroethanol on tyrosinase activity and conformation: inhibition kinetics and computational simulations. Applied Biochemistry Biotechnology 160(7):1896-908 (共同通讯作者) (IF 1.42) 公卫论坛
(4) 陆素颖,李天宇,周宏伟* (2010)头孢噻肟处理的城市河流沉积物微生物群落结构及blaCTX-M多样性的研究。南方医科大学学报30: 463-467.
(5) Wu JY, Jiang XT, Lu SY, Zou F, Zhou HW* (2010) Effects of polymerase, template dilution and cycle number on PCR based 16S rRNA diversity analysis using the deep sequencing method (BMC Microbiology 修回)

公卫家园

(6) Wu JG, Jiang YX, Zha LY, Ye ZM, Zhou ZF, Ye JF, Zhou HW* (2010) Tetracycline degradation by ozonation, and evaluation of biodegradability and toxicity of ozonation byproducts (修回)
(7) Jiang YX, Wu JG, Ai CX, Zou F, Zhou HW* (2010) Integrated lysis protocol can reduced the DNA extraction bias on mangrove soil (Journal of Bioscience and Bioengineering 修回) 公卫家园

其它
(1) Tao R, Ying GG, Su HC, Zhou HW and Sidhuc JPS (2010) Detection of antibiotic resistance and tetracycline resistance genes in Enterobacteriaceae isolated from the Pearl rivers in South China. Environmental Pollution 158: 2101-2109

公卫百科


(2) Li CH, Zhou HW, Wong YS and Tam NF (2009) Vertical distribution and anaerobic biodegradation of polycyclic aromatic hydrocarbons in mangrove sediments in Hong Kong, South China. Science of the Total Environment 407, 5772-5779
(3) Zhong, Y, Luan, TG, Zhou, HW, Lan, CY and Tam, NFY (2006) Pyrene intermediates production in single and binary PAH culture by a PAH-degrading Mycobacterium sp. isolated from mangrove sediment. Environmental Toxicology and Chemistry, 25, 2853-2859
公卫考场

(4) Luan, TG, Yu, KSH, Zhong, Y, Zhou, HW, Lan, CY and Tam, NFY (2006) Study of metabolites from the degradation of polycyclic aromatic hydrocarbons (PAHs) by bacterial consortium enriched from mangrove sediments. Chemosphere, 65, 2289-2296
(5) 张亚莉,周宏伟,马骊等,(2006)医患鼻前庭携带耐甲氧西林金黄色葡萄球菌与医院感染菌同源性的研究。南方医科大学学报, 26, 635-637
公卫家园

(6) Guo, CL, Zhou, HW, Wong, YS and Tam, NFY (2005) Isolation of PAH-degrading bacteria from mangrove sediments and their biodegradation potential. Marine Pollution Bulletin, 51, 1054-1061.
(7) Meng, FG, Zhou, HW, and Zhou, HM (2001) Effects of acrylamide on creatine kinase from rabbit muscle. International Journal of Biochemistry and Cell Biology, 33, 1064-1070
公卫人

联系方式

地址:广州市广州大道北1838号南方医科大学公共卫生与热带医学学院 公卫论坛

邮编:510515 公卫百科

Email: biodegradation@gmail.com
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