项永兵

项永兵 ，男，复旦大学公共卫生学院博士生导师、上海交通大学医学院博士生导师，癌基因及相关基因国家重点实验室课题组长。享受国务院政府特殊津贴（2000年）。

1986年毕业于安徽医科大学获学士学位

1989年毕业于上海医科大学获医学硕士学位

1989-2000年间主要参与和负责了下列流行病学研究课题，例如上海市肿瘤登记处数据管理和统计分析、癌症发病死亡率时间趋势分析、全人群癌症生存率分析、常见癌症病例对照研究（如肺癌、膀胱癌、子宫内膜癌、大肠癌）、膳食和体力活动调查表信度和效度研究、WHO癌症合作中心相关工作等。2000年以来，主要负责一些国际合作项目，例如上海男性健康队列、上海女性健康队列等。此外，2008-2015年主持了国家科技重大专项的子课题（十一五和十二五课题）两项。目前正负责国家重点研发计划项目子项目一项（2016-2020年），参与科技部973项目一项（2015-2019年）。

已在国内外学术期刊上发表了460余篇科研论文，包括中文期刊文章160余篇，英文期刊文章300余篇；其中SCI期刊通讯作者文章46篇（合计IF约195）；此外，作为论文合作者之一，发表下列SCI期刊文章30余篇（如Lancet Oncol、J Natl Cancer Inst、J Clin Oncol、BMJ、N Engl J Med、JAMA Intern Med、Nat Genet、Nat Commun、Gut、Gastroenterology、Plos Med、Diabetes Care等）。已累计培养流行病学与卫生统计学专业研究生30名（博士6名，硕士24名），并带教和培训外籍研究生5位（印尼2人、法国1人和美国2人）。

主要研究方向和内容集中在以下三个方面：一是癌症分布规律和环境致病或危险因素的研究，尤其是生活方式和饮食营养素方面；二是癌症分子流行病学研究，利用生物化学、分子生物学等基础学科技术以及代谢组学等组学手段，在癌症致病机理方面重点开展营养素、生活方式因素等与基因或组学指标交互作用的研究；三是生物统计方法的应用研究，包括临床流行病学、系统综述和meta分析，以及生存分析、描述和分析流行病学中的高级统计方法。

1．肿瘤描述流行病学

2．流行病学现场工作和生物样本资源管理

3．肿瘤等慢性病的病因学探讨

4．生物统计方法及其应用

Zhao LG, Li ZY, Feng GS, Ji XW, Li HL, Tan YT, Gunter MJ, Xiang YB. Coffee drinking and cancer risk: an umbrella review of meta-analysis of observational studies . BMC Cancer  2020 ; 20(1):101 

Zhang W, Wang J, Gao J, Li HL, Han LH, Qing Lan, Nat Rothman, Shu XO, Zheng W, Xiang YB. Prediagnostic level of urinary isoflavonoids in relation to risk of liver cancer in Shanghai, China . Cancer Epidemiol Biomarkers Prev  2019 ; 28(10):1712-1719 

Muller DC, Larose TL, Hodge A, Guida F, Langhammer A, Grankvist K, Meyer K, Cai Q, Arslan AA, Zeleniuch-Jacquotte A, Albanes D, Giles GG, Sesso HD, Lee IM, Gaziano JM, Yuan JM, Hoffman Bolton J, Buring JE, Visvanathan K, Le Marchand L, Purdue MP, Caporaso NE, Midttun ?, Ueland PM, Prentice RL, Weinstein SJ, Stevens VL, Zheng W, Blot WJ, Shu XO, Zhang X, Xiang YB, Koh WP, Hveem K, Thomson CA, Pettinger M, Engstr?m G, Brunnstr?m H, Milne RL, Stampfer MJ, Han J, Johansson M, Brennan P, Severi G, Johansson M. Circulating high sensitivity C reactive protein concentrations and risk of lung cancer: nested case-control study within Lung Cancer Cohort Consortium . BMJ  2019 ; 364:k4981. doi: 10.1136/bmj.k4981 

Nguyen S, Li H, Yu D, Gao J, Gao Y, Tran H, Xiang YB, Zheng W, Shu XO. Adherence to dietary recommendations and colorectal cancer risk: results from two prospective cohort studies . Int J Epidemiol  2019 ; doi: 10.1093/ije/dyz118 

Zhao LG, Shu XO, Li HL, Gao J, Han LH, Wang J, Fang J, Gao YT, Zheng W, Xiang YB  . Prospective cohort studies of dietary vitamin B6 intake and risk of causespecific mortality. . Clin Nutr  2019 ; 38(3):1180-1187 

Lu Y, Kweon SS, Tanikawa C, Jia WH, Xiang YB, Cai Q, Zeng C, Schmit SL, Shin A, Matsuo K, Jee SH, Kim DH, Kim J, Wen W, Shi J, Guo X, Li B, Wang N, Zhang B, Li X, Shin MH, Li HL, Ren Z, Oh JH, Oze I, Ahn YO, Jung KJ, Conti DV, Schumacher FR, Rennert G, Jenkins MA, Campbell PT, Hoffmeister M, Casey G, Gruber SB, Gao J, Gao YT, Pan ZZ, Kamatani Y, Zeng YX, Shu XO, Long J, Matsuda K, Zheng W . Large-scale Genome-wide Association Study of East Asians Identifies Loci Associated With Risk for Colorectal Cancer . Gastroenterology  2019 ; 156(5):1455-1466 

Cui Y, Wen W, Zheng T, Li H, Gao YT, Cai H, You M, Gao J, Yang G, Zheng W, Xiang YB* , Shu XO*. Use of Antihypertensive Medications and Survival of Breast, Colorectal, Lung, or Stomach Cancer . Am J Epidemiol  2019 ; pii: kwz106. doi: 10.1093/aje/kwz106 

Yang JJ, Yu D, Xiang YB, Blot W, White E, Robien K, Sinha R, Park Y, Takata Y, Lazovich D, Gao YT, Zhang X, Lan Q, Bueno-de-Mesquita B, Johansson I, Tumino R, Riboli E, Tj?nneland A, Skeie G, Quirós JR, Johansson M, Smith-Warner SA, Zheng W, Shu XO . Association of Dietary Fiber and Yogurt Consumption With Lung Cancer Risk: A Pooled Analysis . JAMA Oncol  2019 ; doi: 10.1001/jamaoncol.2019.4107 

Li HL, Zhao LG, Wang J, Liu DK, Han LH, Xiang YB. Personal characteristics effects on validation of self-reported type 2 diabetes from a cross-sectional survey among Chinese adults . J Epidemiol  2019 ; doi: 10.2188/jea.JE20190178 

Zuo H, Ueland PM, Midttun ?, Tell GS, Fanidi A, Zheng W, Shu X, Xiang Y, Wu J, Prentice R, Pettinger M, Thomson CA, Giles GG, Hodge A, Cai Q, Blot WJ, Johansson M, Hultdin J, Grankvist K, Stevens VL, McCullough ML, Weinstein SJ, Albanes D, Ziegler RG, Freedman ND, Caporaso NE, Langhammer A, Hveem K, N?ss M, Buring JE, Lee I, Gaziano JM, Severi G, Zhang X, Stampfer MJ, Han J, Zeleniuch-Jacquotte A, Marchand LL, Yuan J, Wang R, Koh W, Gao Y, Ericson U, Visvanathan K, Jones MR, Relton C, Brennan P, Johansson M, Ulvik A . Vitamin B6 catabolism and lung cancer risk: results from the Lung Cancer Cohort Consortium (LC3) . Ann Oncol  2019 ; 30(3):478-485 

Zhu J, Xiang YB, Cai H, Li H, Gao YT, Zheng W, Shu XO. A Prospective Investigation of Dietary Intake and Functional Impairments among the Elderly . Am J Epidemiol  2018 ; 187(11):2372-2386 

Takata Y, Xiang YB, Burk RF, Li H, Hill KE, Cai H, Gao J, Zheng W, Shu XO, Cai Q. Plasma selenoprotein P concentration and lung cancer risk: Results from a case-control study nested within the Shanghai Men's Health Study . Carcinogenesis  2018 ; doi: 10.1093/carcin/bgy103 

Yang Y, Gao J, Tan YT, Li HL, Wang J, Ma X, Zheng W, Shu XO, Xiang YB. Individual and combined effects of hepatitis B surface antigen and viral load on liver cancer risk among hepatitis B carriers . J Gastroen Hepatol   2018 ; May;33(5):1131-1137 

Wu H, Zhou P, Zhang W, Jiang Y, Liu XL, Zhang L, Xia QH*, Xiang YB*  . Time trends of incidence and mortality in colorectal cancer in Changning District of Shanghai, 1975‐ 2013 . J Dig Dis  2018 ; 19﴾9﴿:540‐549 

Sun JW, Zheng W, Li HL, Gao J, Gao YT, Yang G, Lan Q, Rothman N, Shu XO, Xiang YB. Dietary glycemic load, glycemic index, and carbohydrate intake on the risk of lung cancer among men and women in Shanghai . Nutr Cancer   2018 ; May-Jun;70(4):671-677 

Liu X, Xu W, Cai H, Gao YT, Li H, Ji BT, Shu X, Wang T, Gerszten RE, Zheng W, Xiang YB, Shu XO . Green tea consumption and risk of type 2 diabetes in Chinese adults: the Shanghai Women's Health Study and the Shanghai Men's Health Study . Int J Epidemiol  2018 ; doi: 10.1093/ije/dyy173 

Yu D, Zheng W, Johansson M, Lan Q, Park Y, White E, Matthews CE, Sawada N, Gao YT, Robien K, Sinha R, Langhammer A, Kaaks R, Giovannucci EL, Liao LM, Xiang YB, Lazovich D, Peters U, Zhang X, Bueno-de-Mesquita B, Willett WC, Tsugane S, Takata Y, Smith-Warner SA, Blot W, Shu XO . Overall and Central Obesity and Risk of Lung Cancer: A Pooled Analysis . J Natl Cancer Inst  2018 ; 110(8):831-842 

Shu X, Xiang YB, Rothman N, Yu D, Li HL, Yang G, Cai H, Ma X, Lan Q, Gao YT, Jia W, Shu XO, Zheng W. Prospective study of blood metabolites associated with colorectal cancer risk . Int J Cancer  2018 ; doi: 10.1002/ijc.31341 

Shu X, Zheng W, Yu D, Li H, Lan Q, Yang G, Cai H, Ma X, Rothman N, Gao YT, Jia W, Xiang YB, Shu XO. Prospective metabolomics study identifies potential novel blood metabolites associated with pancreatic cancer risk . Int J Cancer  2018 ; 143(9):2161-2167 

王静, 李泓澜, 马骁, 韩丽华, 方婕, 高立峰, 舒晓鸥, 项永兵  . 十字花科蔬菜和肺癌关系的巢式病例对照研究. 中华预防医学杂志  2018 ; 52(8):816-821 

Zhang QL, Zhao LG, Li HL, Gao J, Yang G, Wang J, Zheng W, Shu XO, Xiang YB. The joint effects of major lifestyle factors on colorectal cancer risk among Chinese men: a prospective cohort study . Int J Cancer   2018 ; Mar 15;142(6):1093-1101 

唐卫国, 舒晓鸥, 高静, 李泓澜, 张薇, 方婕, 高立峰, 刘大可, 郑苇, 项永兵. 膳食大豆食物摄入与全肿瘤死亡风险关系的前瞻性队列研究 . 肿瘤  2017 ; 37(4):350-358 

Zhao LG, Shu XO, Li HL, Zhang W, Gao J, Sun JW, Zheng W, Xiang YB. Dietary antioxidant vitamins intake and mortality: A report from two cohort studies of Chinese adults in Shanghai . J Epidemiol.  2017 ; 27(3):89-97 

Yang JJ, Yu D, Takata Y, Smith-Warner SA, Blot W, White E, Robien K, Park Y, Xiang YB, Sinha R, Lazovich D, Stampfer M, Tumino R, Aune D, Overvad K, Liao L, Zhang X, Gao YT, Johansson M, Willett W, Zheng W, Shu XO . Dietary Fat Intake and Lung Cancer Risk: A Pooled Analysis . J Clin Oncol  2017 ; JCO2017733329 

Zhang QL, Zhao LG, Zhang W, Li HL, Gao J, Han LH, Zheng W, Shu XO, Xiang YB. Combined Impact of Known Lifestyle Factors on Total and Cause-Specific Mortality among Chinese Men: A Prospective Cohort Study . Sci Rep  2017 ; 13;7(1):5293 

Zhao LG, Li HL, Sun JW, Yang Y, Ma X, Shu XO, Zheng W, Xiang YB. Green tea consumption and all-cause mortality: results from two Chinese cohort study . J Epidemiol  2017 ; 27(1):36–41 

张庆丽, 郑苇, 李泓澜, 高静, 方婕, 高立峰, 刘大可,舒晓鸥, 项永兵. 健康生活方式指数与男性胃癌关系的前瞻性队列研究 . 中华预防医学杂志  2017 ; 51(5): 386-392 

项永兵. 生存分析 . 见: 徐望红(主编)，肿瘤流行病学  2017 ; 上海: 复旦大学出版社, 2017.6, P269-280  

项永兵. 肿瘤登记 . 见: 徐望红(主编), 肿瘤流行病学  2017 ; 上海: 复旦大学出版社, 2017.6，P89-99 

Ma X, Yang Y, Li HL, Zheng W, Gao J, Zhang W, Yang G, Shu XO, Xiang YB. Dietary trace element intake and liver cancer risk: results from two population-based cohorts in China . Int J Cancer  2017 ; 140(5):1050-1059