RStudio
RStudio runs on all major desktop platforms (Windows, Mac OS X, Ubuntu, or Fedora) and can also run as a server which enables multiple users to access the IDE using a web browser.
A couple of screenshots (click here for more screenshots):
The version of RStudio available today is a beta (v0.92) and is released under the GNU AGPL license. We’re hoping for lots of input and dialog with the R community to help make the product as good as it can be!
More details on the project as well as download links can be found at: http://www.rstudio.org.