高友鹤
研究方向
尿蛋白质组;器官功能;蛋白质相互作用;生物信息学
公卫人
主要学习及工作简历
1982.9-1990.7 公卫考场 | 中国协和医科大学 公卫考场 | 医学博士 公卫家园 |
1990.7-1997.1 公卫人 | 美国康涅狄格大学 公卫家园 | 生物学博士
公卫百科 |
1997.1-2001.7 公卫人 | 美国哈佛医学院 公卫家园 | 博士后,讲师 公卫人 |
2001.7- 公卫百科 | 中国医学科学院基础医学研究所 公卫家园 | 教授
公卫考场 |
社会任职
国务院学位委员会基础医学组成员
公卫考场
公卫考场
代表性学术论文 公卫人
(1)A strategy for studying the liver secretome on the organ level Yang Zhang, Yan Wang, Wei Sun, Lulu Jia, Sucan Ma and Youhe Gao* Journal of Proteome Research
http://pubs.acs.org/doi/abs/10.1021/pr901057k?prevSearch=youhe%2Bgao&searchHistoryKey
公卫百科
(2)Siqi Hu, Eli Song, Rui Tian, Sucan Ma, Tao Yang, Yi Mu, Yuan Li, Chen Shao, and Youhe Gao (2009)Systematic analysis of a simple adaptor protein PDZK1: ligand identification, interaction and functional prediction of complex. Cellular Physiology and Biochemistry 24:231–242 公卫人
(3)Lulu Jia1, Ling Zhang1, Chen Shao1, Eli Song1, Wei Sun1, Mingxi Li2, and Youhe Gao1§ (2009)An attempt to understand kidney’s protein handling function by comparing plasma and urine proteomes Plos One 4(4):e5146
(4)Yong Chen, Bei Gu, Shuzhen Wu, Wei Sun, Sucan Ma, Yuqin Liu* and Youhe Gao* (2009)Using Enrichment Index for Quality Control of Secretory Protein Sample and Identification of Secretory Proteins Journal of Mass Spectrometry 44(3):397-403 公卫考场
(5)Chen Shao, Wei Sun, Fuxin Li, Ruifeng Yang, Ling Zhang and Youhe Gao (2009)Oscore: a combined score to reduce false negative rate for peptide identification in tandem mass spectrometry analysis Journal of Mass Spectrometry 44(1):25-31
(6)Wei Sun1,5, Yong Chen1,5, Fuxin Li2, Ling Zhang3, Ruifeng Yang4, Zhi Zhang4, Dexian Zheng1, Youhe Gao1 (2009)Dynamic urinary proteomic analysis reveals stable proteins to be potential biomarkers Proteomics- clinical application 3(3):370-382 公卫论坛
(7)Wei Sun, Ruifeng Yang, Ling Zhang, Chen Shao, Zhengguo Zhang and Youhe Gao (2009) Improve peptide identification by empirical peptide retention time database Rapid Communication in Mass Spectrometry 23(1):109-118
(8)Yan Wang; Yong Chen; Yang Zhang; Shuzhen Wu; Sucan Ma; Siqi Hu; Ling Zhang; Chen Shao; Mingxi Li and Youhe Gao (2008) Differential ConA-enriched Urinary Proteome in Rat Experimental Glomerular Diseases Biochemical and Biophysical Research Communications 4;371(3):385-90.
公卫人
(9)Eli Song, Shijuan Gao, Rui Tian, Sucan Ma, Haiming Huang, Jiayan Guo, Yingna Li, Ling Zhang, and Youhe Gao (2006)A high-efficiency strategy for binding property characterization of peptide-binding domains. Molecular & Cellular Proteomics 5:1368-1381
公卫考场
(10)Ling Zhang*, Chen Shao*, Dexian Zheng and Youhe Gao (2006)An integrated machine learning system to computationally screen protein databases for Protein binding peptide ligands with generalization capability Molecular & Cellular Proteomics 5: 1224-1232. 公卫百科
(11)Wei Sun, Shijuan Gao, Linjie Wang, Yong Chen, Shuzhen Wu, Xiaorong Wang, Dexian Zheng, and Youhe Gao (2006)Microwave-assisted protein preparation and enzymatic digestion in proteomics Molecular & Cellular Proteomics 5:769-776
(12)Linjie Wang, Fuxin Li, Wei Sun, Shuzhen Wu, Xiaorong Wang, Ling Zhang, Dexian Zheng, Jue Wang and Youhe Gao (2006)Concanavalin A captured glycoproteins in healthy human urine Molecular & Cellular Proteomics 5: 560-562.
(13)Wei Sun, Shuzhen Wu, Xiaorong Wang, Fuxin Li, Jue Wang, Dexian Zheng, and Youhe Gao (2005) Human urine proteome analysis with three different separation approaches Proteomics 5(18)4994-5001 公卫论坛
(14)Haiming Huang and Youhe Gao (2005) A method for the generation of arbitrary peptide libraries. Molecular Biotechnology 30(2):135-142
(15)Wei Sun, Fuxin Li, Jue Wang, Dexian Zheng and Youhe Gao (2004) AMASS: Software for automatically validating the quality of MS/MS spectrum from SEQUEST results. Molecular & Cellular Proteomics, 3: 1194 - 1199.
公卫考场
(16)Fuxin Li 1*, Wei Sun 2, Youhe Gao 2* Jue Wang1 (2004)RScore: A Peptide Randomicity Score For Evaluating MS/MS Spectra. Rapid Communication in Mass Spectrometry 18(14): 1655-9 公卫论坛
主编或副主编的著作/译著
公卫家园
公卫论坛
Renal and Urinary Proteomics Methods and Protocols 公卫论坛 | Wiley
公卫家园 | Thongboonkerd, Visith 公卫家园 | 2009 公卫考场 |
公卫人
公卫家园
重要奖项
公卫考场
美国生物化学分子生物学学会(ASBMB) 公卫百科 | 学生旅行奖 公卫人 | 2006 两人 |
国际生物化学与分子生物学联盟(IUBMB)
公卫家园 | 学生旅行奖 公卫百科 | 2006
公卫百科 |
第七届国际健康与生命科学中的质谱(Seventh International Symposium on Mass Spectrometry in the Health and Life Sciences) 公卫考场 | 会议旅行奖
公卫家园 | 2005 公卫论坛 |
全国优秀博士学位论文 公卫考场 | 公卫论坛 | 2007 公卫家园 |
亚太蛋白质组学大会(AOHUPO)
公卫论坛 | 学生旅行奖 公卫论坛 | 2008
公卫考场 |
联系方式
邮箱:gaoyouhe@pumc.edu.cn
公卫百科
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